Reserve concomitant prescribing of such medications in sufferers for whom other procedure selections are insufficient. Restrict dosages and durations towards the minimal necessary. Keep an eye on closely for signs of respiratory depression and sedation.Lonafarnib might increase the AUC and peak concentration of CYP2C19 substrates. If coadministrati

methylprednisolone will decrease the level or influence of diazepam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.Adjunct use, if apprehension, anxiousness or acute tension reactions present before endoscopic techniquesMonitor for indications of respiratory depression That could be larger than usually expected and de